cm 1244 (ATCC)
94
Structured Review
ATCC
cm 1244
Cm 1244, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cm+1244/CCD-1136Sk/10__1128_slash_aac__49__5__2119___2121__2005-90-72-18
Average 94 stars, based on 12 article reviews
Cm 1244, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cm+1244/CCD-1136Sk/10__1128_slash_aac__49__5__2119___2121__2005-90-72-18
Average 94 stars, based on 12 article reviews
cm 1244 - by Bioz Stars,
2026-10
94/100 stars
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Isolation:Article Title: Differences in Interactions between Azole Drugs Related to Modifications in the 14-α Sterol Demethylase Gene ( cyp51A ) of Aspergillus fumigatus Article Snippet: This hypothesis was reinforced by the fact that all combinations show indiffer- Strainc CYP51A amino acid MIC ( g/ml)a FIC (interpretation)b Group 54 220 ITC VRC FLC ITC-FLC ITC-VRC VRC-FLC CM-237 S G M 0.25 0.50 640 0.917 (I) 0.430 (S) 0.750 (I) ATCC 9197 S G M 0.50 0.50 640 0.708 (I) 0.522 (I) 0.750 (I) CM-2121 S G M 0.25 0.50 640 0.750 (I) 0.503 (I) 0.880 (I) CM-2127 S G M 0.50 0.50 1,280 0.917 (I) 0.511 (I) 1.000 (I) CM-2198 S G M 0.25 0.50 640 0.875 (I) 0.461 (S) 0.750 (I) CM-2120 S G M 1.00 0.50 640 0.917 (I) 0.386 (S) 0.880 (I) ATCC 204305 S G M 0.25 0.25 640 0.750 (I) 0.490 (S) 0.630 (I) CM-2194 S G M 0.50 1.00 1,280 0.710 (I) 0.610 (I) 0.610 (I) CM-2705d A-KO 0.06 0.50 80 0.940 (I) 0.730 (I) 0.660 (I) CM-2707e A-KO 0.06 0.25 160 0.880 (I) 0.750 (I) 0.870 (I) CM-2706f B-KO G M 0.25 0.50 640 1.000 (I) 1.000 (I) 0.500 (I) CM-2162 G54 V M 16 0.25 160 0.240 (S) 0.190 (S) 0.830 (I) CM-1244 G54 E M 16 0.25 160 0.177 (S) 0.258 (S) 1.190 (I) CM-2160 G54 E M 16 0.50 320 0.273 (S) 0.227 (S) 1.340 (I) CM-2161 G54 E M 16 0.50 160 0.266 (S) 0.227 (S) 0.920 (I) CM-2697g G54 E M 16 0.50 160 0.177 (S) 0.190 (S) 0.520 (I) CM-2698g G54 E M 16 0.25 80 0.216 (S) 0.263 (S) 0.520 (I) CM-2699h G54 E M 16 0.50 320 0.193 (S) 0.170 (S) 0.520 (I) CM-2097 G54 R M 16 0.50 160 0.156 (S) 0.177 (S) 1.250 (I) CM-2700h G54 R M 16 0.25 160 0.096 (S) 0.193 (S) 0.590 (I) CM-2701h G54 R M 16 0.25 160 0.085 (S) 0.115 (S) 0.590 (I) CM-2702h G54 R M 16 0.50 160 0.188 (S) 0.146 (S) 0.560 (I) CM-2266 G54 W M 16 0.50 1,280 0.526 (I) 0.172 (S) 1.170 (I) CM-1245 M220 G V 16 1.00 1,280 2.000 (I) 0.295 (S) 2.000 (I) CM-1252 M220 G V 16 1.00 1,280 2.000 (I) 0.219 (S) 2.000 (I) CM-2158 M220 G V 16 2.00 1,280 2.000 (I) 0.219 (S) 2.000 (I) CM-2159 M220 G K 16 2.00 1,280 2.000 (I) 0.341 (S) 2.150 (I) CM-2164 M220 G T 16 1.00 1,280 2.000 (I) 0.263 (S) 2.000 (I) CM-2709g M220 G K 16 2.00 1,280 2.000 (I) 0.439 (S) 1.750 (I) CM-2713g M220 G V 16 1.00 1,280 2.000 (I) 0.219 (S) 2.000 (I) CM-2735g M220 G T 16 1.00 1,280 2.000 (I) 0.169 (S) 1.750 (I) a Geometric mean (three repetitions on three separate days). b Arithmetic mean (three repetitions on three separate days). .. S, synergistic; I, indifferent. c Strains are clinical isolates except as noted otherwise, with the exception of the ATCC strains. d CM-2705 is a cyp51A gene-knockout strain with CM-237 as the parental strain. e CM-2707 is a cyp51A gene-disrupted strain with CM-1252 as the parental strain. f CM-2706 is a cyp51B gene-knockout strain with CM-237 as the parental strain. g Gene replacement of the CM-237 wild-type cyp51A gene with the mutated strain Selection:Article Title: Differences in Interactions between Azole Drugs Related to Modifications in the 14-α Sterol Demethylase Gene ( cyp51A ) of Aspergillus fumigatus Article Snippet: This hypothesis was reinforced by the fact that all combinations show indiffer- Strainc CYP51A amino acid MIC ( g/ml)a FIC (interpretation)b Group 54 220 ITC VRC FLC ITC-FLC ITC-VRC VRC-FLC CM-237 S G M 0.25 0.50 640 0.917 (I) 0.430 (S) 0.750 (I) ATCC 9197 S G M 0.50 0.50 640 0.708 (I) 0.522 (I) 0.750 (I) CM-2121 S G M 0.25 0.50 640 0.750 (I) 0.503 (I) 0.880 (I) CM-2127 S G M 0.50 0.50 1,280 0.917 (I) 0.511 (I) 1.000 (I) CM-2198 S G M 0.25 0.50 640 0.875 (I) 0.461 (S) 0.750 (I) CM-2120 S G M 1.00 0.50 640 0.917 (I) 0.386 (S) 0.880 (I) ATCC 204305 S G M 0.25 0.25 640 0.750 (I) 0.490 (S) 0.630 (I) CM-2194 S G M 0.50 1.00 1,280 0.710 (I) 0.610 (I) 0.610 (I) CM-2705d A-KO 0.06 0.50 80 0.940 (I) 0.730 (I) 0.660 (I) CM-2707e A-KO 0.06 0.25 160 0.880 (I) 0.750 (I) 0.870 (I) CM-2706f B-KO G M 0.25 0.50 640 1.000 (I) 1.000 (I) 0.500 (I) CM-2162 G54 V M 16 0.25 160 0.240 (S) 0.190 (S) 0.830 (I) CM-1244 G54 E M 16 0.25 160 0.177 (S) 0.258 (S) 1.190 (I) CM-2160 G54 E M 16 0.50 320 0.273 (S) 0.227 (S) 1.340 (I) CM-2161 G54 E M 16 0.50 160 0.266 (S) 0.227 (S) 0.920 (I) CM-2697g G54 E M 16 0.50 160 0.177 (S) 0.190 (S) 0.520 (I) CM-2698g G54 E M 16 0.25 80 0.216 (S) 0.263 (S) 0.520 (I) CM-2699h G54 E M 16 0.50 320 0.193 (S) 0.170 (S) 0.520 (I) CM-2097 G54 R M 16 0.50 160 0.156 (S) 0.177 (S) 1.250 (I) CM-2700h G54 R M 16 0.25 160 0.096 (S) 0.193 (S) 0.590 (I) CM-2701h G54 R M 16 0.25 160 0.085 (S) 0.115 (S) 0.590 (I) CM-2702h G54 R M 16 0.50 160 0.188 (S) 0.146 (S) 0.560 (I) CM-2266 G54 W M 16 0.50 1,280 0.526 (I) 0.172 (S) 1.170 (I) CM-1245 M220 G V 16 1.00 1,280 2.000 (I) 0.295 (S) 2.000 (I) CM-1252 M220 G V 16 1.00 1,280 2.000 (I) 0.219 (S) 2.000 (I) CM-2158 M220 G V 16 2.00 1,280 2.000 (I) 0.219 (S) 2.000 (I) CM-2159 M220 G K 16 2.00 1,280 2.000 (I) 0.341 (S) 2.150 (I) CM-2164 M220 G T 16 1.00 1,280 2.000 (I) 0.263 (S) 2.000 (I) CM-2709g M220 G K 16 2.00 1,280 2.000 (I) 0.439 (S) 1.750 (I) CM-2713g M220 G V 16 1.00 1,280 2.000 (I) 0.219 (S) 2.000 (I) CM-2735g M220 G T 16 1.00 1,280 2.000 (I) 0.169 (S) 1.750 (I) a Geometric mean (three repetitions on three separate days). b Arithmetic mean (three repetitions on three separate days). .. S, synergistic; I, indifferent. c Strains are clinical isolates except as noted otherwise, with the exception of the ATCC strains. d CM-2705 is a cyp51A gene-knockout strain with CM-237 as the parental strain. e CM-2707 is a cyp51A gene-disrupted strain with CM-1252 as the parental strain. f CM-2706 is a cyp51B gene-knockout strain with CM-237 as the parental strain. g Gene replacement of the CM-237 wild-type cyp51A gene with the mutated strain |